硅纳米线阵列电极作为细胞色素c传感器的研究

利用化学刻蚀法由p型硅片制备了硅纳米线阵列,经过表面去氧化层处理后,制备了检测蛋白质细胞色素c的电化学传感器.实验表明,硅纳米线阵列电极对细胞色素c有良好的电化学响应,并且在低浓度条件下具备线性响应的特点.根据与未经表面处理的硅纳米线阵列电极的实验结果相对比,提出了细胞色素c所具备的羧基末端与硅纳米线阵列电极表面的Si-H相互作用从而改善传感性能的检测机理.

Silicon Nanowire Arrays as Electrochemical Biosensors for Cytochrome c

The direct electrochemical biosensor for cytochrome c based on the silicon nanowire arrays was fabricated.The silicon nanowire arrays were prepared from the etched silicon wafer,which were then treated with aqua regia and HF to remove the cladding silicon oxide sheath.The modified silicon nanowire arrays were further used as the electrode for fabricating the direct electrochemical biosensors for the detection of cytochrome c,which exhibited linear response to cytochrome c at low concentration and high sensitivity of 2.75 μA·mmol-1·L due to the vast surface-to-bulk ratio of the silicon nanowire arrays and the interaction between the carboxyl group of cytochrome and Si-H group provided by the surface of the modified silicon nanowire arrays.