Abstract: | Oligomeric N-acetyl-L-glutamic acid benzyl esters with exact residue number (2, 3 or 4) have been synthesized by a stepwise procedure. The aggregational behavior of these oligomeric molecules in dioxane and benzene has been investigated by use of 1H NMR. In particular, the concentration dependence of the 1H signals for the N-terminal CH3 protons has provided evidence that an intermolecular CH3···? interaction plays a critical role in the formation of aggregates and that an intramolecular CH3···? interaction occurs in the monomolecular state. |