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Dual-Channel Electrospray Microchip
Authors:Yu Lu  Fang Liu  Niels Lion  Hubert H Girault
Institution:1. Laboratoire d’Electrochimie Physique et Analytique, Station 6, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Lausanne, Switzerland
2. Service Regional Vaudois de Transfusion sanguine, Epalinges, Switzerland
Abstract:A dual-channel electrospray microchip has been developed for electrospray ionization mass spectrometry (ESI-MS) where aqueous samples are mixed at the Taylor cone with an organic buffer. Due to the fast and effective mixing in the Taylor cone, the aqueous sample can be well ionized with a high ion intensity. The influence of geometric parameters such as the distance between the two microchannels at their junction at the tip of the emitter has been investigated together with chemical parameters such as the organic buffer composition. ></img>                                </span>                              </span></td>
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