Regioselective synthesis of 4-aryl-3,4-dihydro-1,3,5-triazino[2,1-<Emphasis Type="Italic">a</Emphasis>]isoindol-2-ones |
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| Authors: | Angelina V Biitseva Olha V Hordiyenko Volodymyr A Sukach Myhailo V Vovk Konstantin A Pichugin Irina S Konovalova Oleg V Shishkin |
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| Institution: | (1) Chemistry Department, Kyiv National Taras Shevchenko University, Kyiv, Ukraine;(2) Institute of Organic Chemistry, National Academy of Sciences, Kyiv, Ukraine;(3) STC “Institute for Single Crystals”, National Academy of Sciences, Kharkiv, Ukraine |
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| Abstract: | The condensation of binucleophilic 3-amino-1-arylimino-1H-isoindoles with bifunctional 1-chloro-benzylisocyanates occurs regioselectively resulting in 3,4-dihydro-1,3,5-triazino2,1-a]isoindol-2-one derivatives. The structures of the synthesized compounds were unambiguously established by NOE experiments.
Correspondence: Olha V. Hordiyenko, Chemistry Department, Kyiv National Taras Shevchenko University, 01033 Kyiv, Ukraine. |
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| Keywords: | Heterocycles Cyclizations NMR Spectroscopy 3-Amino-1-arylimino-1H-isoindoles 4-Aryl-3 4-dihydro-1 3 5-triazino[2 1-a]isoindol-2-ones |
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