C-C bond-forming desulfurizations of sulfoximines |
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Authors: | Reggelin M Slavik S Bühle P |
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Institution: | Clemens-Sch?pf-Insitut für Organische Chemie and Biochemie, Petersenstrasse 22, Technische Universit?t, 64287 Darmstadt, Germany. re@punk.oc.chemie.tu-darmstadt.de |
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Abstract: | Highly substituted, enantiomerically pure azaheterocyclic ring systems play an important role in medicinal chemistry as potential peptide mimetics. Metalated 2-alkenyl sulfoximines offer an efficient entry to this class of compounds. In this paper, we describe a new means to remove the sulfonimidoyl auxiliary with concomitant formation of a C-C double bond. |
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