A supramolecular approach to multivalent target-specific MRI contrast agents for angiogenesis |
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| Authors: | Dirksen Anouk Langereis Sander de Waal Bas F M van Genderen Marcel H P Hackeng Tilman M Meijer E W |
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| Institution: | Laboratory of Macromolecular and Organic Chemistry, Eindhoven University of Technology, Eindhoven, The Netherlands. |
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| Abstract: | The synthesis of a cyclic peptide-Gd(III)DTPA molecule equipped with biotin is presented, yielding a well-defined multivalent MRI contrast agent after its coupling to avidin. |
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