INHIBITION OF NUCLEIC ACID SYNTHESIS IN CELLS EXPOSED TO 200 MICROMETER RADIATION FROM THE FREE ELECTRON LASER |
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| Authors: | Michael W. Berns William Bewley |
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| Affiliation: | Department of Surgery, Beckman Laser Institute and Medical Clinic, University of California, Irvine, California 92717;Department of Physics, University of California Santa Barbara, California 93106 |
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| Abstract: | Vertebrate tissue culture cells were exposed to 200 um wavelength radiation (1CO W/cm2) from a free electron laser (FEL) of the electrostatic generator type. Cell cultures demonstrated no morphological alterations but a statistically significant (P .05) proportion of the cells exhibited inhibition of DNA synthesis. This study demonstrates the first biological effects of the FEL and the feasibility of performing biological investigations with this device. |
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