The application of 2-(4-chlorophenyl)-sulfonylethoxycarbonyl (CPSEC) group in the synthesis of a DNA segment using the phosphotriester approach |
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Authors: | Staffan Josephson Neil Balgobin Jyoti Chattopadhyaya |
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Institution: | Department of Microbiology, Box 581, The Biomedical Centre, Uppsala University S-751 23 Uppsala, Sweden |
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Abstract: | The new base labile CPSEC group has been successfully employed for the protection of the 5′-hydroxyl function to synthesize a “universal Stop codon” DNA sequence: 5′d(TCAATCAATCA)3′. |
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