| A Novel Synthesis of Isoxazole Derivatives |
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| 作者姓名： | Jun Feng WANG Bao Shan DU Qing Hua CHEN |
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| 作者单位： | Department of Chemistry，Beijing Normal University，Beijing 100875 |
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| 摘 要： | Thenitronesareveryimportantinorganicsynthesis.TheyhavebeenwidelyutilizedasintermediatesfromwhichcomPlexheterocyclicornaturalcompoundsanddrugs"'weresynthesisedsuchasisoxazoline3andoxazine4.However,theconversionofnitronetoisoxazolebythermaldecompositionhasnotbeenreported.Inthispaper,wedevelopanewsyntheticmethodofisoxazolesfromheterocyclicnitronesasfollows:wi.-"'rtXfa.H;b.3,4-O-CH2-o-;c.4-CH3O,d.4-Cl;e.2-Brf.2-Cl,g.3,4-coCH3;h.3-ro2;i.4-so2;j.4-CH3Experiment8lAdriedroundbottomflaskundernit…
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A Novel Synthesis of Isoxazole Derivatives |
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| Jun Feng WANG, Bao Shan DU, Qing Hua CHEN.A Novel Synthesis of Isoxazole Derivatives[J].Chinese Chemical Letters,1998(9). |
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| Authors: | Jun Feng WANG Bao Shan DU Qing Hua CHEN |
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| Abstract: | The new synthetic method of isoxazole derivatives was succesfully achieved. Theexperimental results demonstrate that thermal decomposition reactions of nitrone could take placewith yields of 41-81%, to give a series of new isoxazole derivatives. |
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| Keywords: | nitrone isoxazole |
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