Die Synthese von 4-Alkylchinuclidinen. Chinuclidinreihe, 11. Mitteilung |
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Authors: | C. A. Grob W. Simon W. D. Treffert |
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Abstract: | The syntheses of 4-methyl-, 4-ethyl-, 4-isopropyl-and 4-t-butylquinuclidine are described. The key step in the synthesis of 4-t-butylquinuclidine involves a modified Koch-Haaf reaction leading from a δ-amino-tert. alcohol to an ester of the homologous acid. |
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