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高龄五指山小型猪近交系血液生化指标测定
引用本文:黄雷,牟玉莲,杨述林,王辰,程玉柱,徐盼,冯书堂.高龄五指山小型猪近交系血液生化指标测定[J].实验动物科学,2013(5):44-47.
作者姓名:黄雷  牟玉莲  杨述林  王辰  程玉柱  徐盼  冯书堂
作者单位:中国农业科学院北京畜牧兽医研究所,北京100193
基金项目:国家科技支撑(No.2012BAI3904);国家重点基础研究发展计划(973计划)(No.2011CB944202)
摘    要:目的 了解猪龄和性别对五指山小型猪(WZSP)近交系血液生化指标的影响.方法 WZSP近交系F17、F186月龄青年猪34头(7 ♂,27♀),5-6高龄猪21头(8 ♂,13♀),禁食12 h后经由前腔静脉采血,用全自动生化分析仪检测血液生化指标.结果 青年猪和高龄猪有部分血液生化指标具有性别差异(P<0.05),其中青年猪有3项高龄猪有7项;青年猪和高龄猪有16项血清生化指标具有差异(P<0.05).结论 WZSP近交系血液生化指标有着明显的年龄差异,这对选用高龄猪作为人类老年化动物模型提供了基础参考数据.

关 键 词:五指山小型猪  生化指标  高龄猪

Blood Biochemical Tests of Senior Inbred Wuzhishan Miniature Pigs
HUANG Lei,MU Yu-lian,YANG Shu-lin,WANG Chen,CHENG Yu-zhu,XU Pan,FENG Shu-tang.Blood Biochemical Tests of Senior Inbred Wuzhishan Miniature Pigs[J].Shiyan Dongwu Kexue,2013(5):44-47.
Authors:HUANG Lei  MU Yu-lian  YANG Shu-lin  WANG Chen  CHENG Yu-zhu  XU Pan  FENG Shu-tang
Institution:1.Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China;)
Abstract:Objective To analysis the blood biochemical parameters influenced by age and gender of inbreed Wuzhishan miniature pigs.Method 34 6-month-old pigs (7 ♂,27 ♀),as well as 21 pigs of 5-6 years old(8 ♂,13 ♀)from F17,F18 offsprings of inbred WZSP were selected.After 12 hours of fasting,blood was collected via the superior vena cava and biochemical indexes were analyzed by full-Automatic biochemical analyzer.Result In all the blood biochemical indexes,3 of them showed gender differences (P < 0.05) between young pigs,while 7 of them showed gender differences (P < 0.05) among aged pigs.Meanwhile 16 of the blood biochemical indexes showed age differences (P < 0.05).Conclusion The blood biochemical indexes of WZSP inbred lines display a significant age difference (P < 0.05).This provides a basic reference data for choosing the aged miniature pigs as human aging animal models.
Keywords:Wuzhishan miniature pig  biochemical index  senior pig
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