A Simple Stereoselective Synthesis of Aplysinopsin Analogs |
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| Authors: | Lovro Selič ,Renata Jakš e,Kristina Lampič ,Ljubo Golič ,Simona Golič ‐Grdadolnik,Branko Stanovnik |
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| Abstract: | Simple and stereoselective syntheses of aplysinopsins and their analogs from either methyl 2‐[(2,2‐disubstituted ethenyl)amino]‐3‐(dimethylamino)prop‐2‐enoates 11 or 5‐[(dimethylamino)methylidene]imidazolidine‐2,4‐diones 20 are described. The structures of products are established by 1H‐ and 13C‐NMR, and NOESY spectroscopy, and X‐ray crystal‐structure analysis. |
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