Potentiometric enzyme electrode for uric acid.

An enzyme electrode for uric acid, with immobilized uricase on a pCO₂ membrane electrode, is described. Evaluation studies show that the enzyme electrode attains performance characteristics similar to homogeneous enzymatic conversion of uric acid under optimum solution conditions. Comparison of analyses carried out with the enzyme electrode and classical procedures on urine control samples demonstrates acceptable accuracy and precision for the electrode method.