A new [4]carceplex, and a crystal structure and dynamic combinatorial chemistry of a [5]carceplex |
| |
Authors: | Jianyu Sun |
| |
Institution: | Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, Canada V6T 1Z1 |
| |
Abstract: | A new 4]carceplex (2·guest) is reported. It is composed of two cavitands linked by four disulfide bonds. It forms twistomers, which interconvert on a millisecond timescale. The energy barrier for interconversion of twistomers is guest-dependent. Formation of 4]carceplex 2·guest is template dependent. The selectivity in templates is flat relative to most previous related template work. Larger kin 5]carceplex 1·guests were reinvestigated. A crystal structure confirms the twist between the hemispherical cavitands. Use of a redox buffer allowed dynamic combinatorial chemistry to be performed between pairs of templates. |
| |
Keywords: | Carceplex Supramolecular Disulfide Dynamic combinatorial chemistry Guest release |
本文献已被 ScienceDirect 等数据库收录! |