Highly efficient synthesis of 2,3-dihydroquinazolin-4(1H)-ones catalyzed by heteropoly acids in water |
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| Authors: | YingXiao Zong Yan Zhao WenCai Luo Xing Hai Yu Jun Ke Wang Yi Pan |
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| Affiliation: | a Key Laboratory of Resources and Environment, Chemistry of West China, Hexi University, Zhangye 734000, China;b School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China |
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| Abstract: | Heteropoly acids efficiently catalyzed the cyclocondensation reaction of anthranilamide with aldehydes in water at ambient temperature and afforded the corresponding 2, 3-dihydro-4(1H)-quinazolinones compounds in good to excellent yields. This method provides mild reaction conditions and clean reaction profiles, using a small quantity of catalyst and a simple workup procedure. |
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| Keywords: | Heteropoly acid 2,3-Dihydroquinazolin-4(1H)-ones Water |
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