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One-pot, four-component reaction of isocyanides, dimethyl acetylenedicarboxylate, and cyclobutene-1,2-diones: a synthesis of novel spiroheterocycles
Authors:Vijay Nair  Rajeev S Menon  Ani Deepthi  B Rema Devi  AT Biju
Institution:Regional Research Laboratory (CSIR), Trivandrum 695 019, India
Abstract:Isocyanides, dimethyl acetylenedicarboxylate, and cyclobutene-1,2-diones react in one-pot to afford novel spirocyclic compounds with double insertion of the isocyanide.
Keywords:Multicomponent reactions  Isocyanides  Zwitterions  Dimethyl acetylenedicarboxylate
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