An environmentally friendly procedure for Mukaiyama aldol and Mukaiyama-Michael reactions using a catalytic amount of DBU under solvent- and metal-free conditions |
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| Authors: | Zhi-Liang Shen Shun-Jun Ji Teck-Peng Loh |
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| Affiliation: | a Department of Chemistry, 3 Science Drive 3, National University of Singapore, Singapore 117543, Singapore
b Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering of Suzhou University, Suzhou 215006, China |
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| Abstract: | Mukaiyama aldol and Mukaiyama-Michael reactions can proceed smoothly in the presence of a catalytic amount of DBU (20% mmol), to afford the corresponding products in moderate to good yields. This solvent- and metal-free approach provides an environmentally friendly procedure for Mukaiyama reactions. |
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| Keywords: | Mukaiyama reaction DBU Organic catalyst Solvent-free condition Metal-free |
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