Microwave-assisted cross-coupling of 3-chloro-2-pyrazolines and 3-chloro-1-phenyl-1,4,5,6-tetrahydropyridazine with aryl boronic acids |
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| Authors: | Hong-Jun Wang Jeffrey Keilman Zhen-Jia Chen |
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| Affiliation: | a Albany Molecular Research, Inc., Bothell Research Center, 18804 North Creek Parkway, Bothell, WA 98011, USA
b Department of Combinatorial/Parallel Synthesis, Albany Molecular Research, Inc., P.O. Box 15098, 21 Corporate Circle, Albany, NY 12212-5098, USA |
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| Abstract: | 3-Chloro-1-phenyl-2-pyrazoline and 3-chloro-1-phenyl-1,4,5,6-tetrahydropyridazine were coupled with aryl boronic acids in good yields under microwave heating conditions (140 °C, 5 min). |
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| Keywords: | 2-Pyrazoline 1,4,5,6-Tetrahydropyridazine Palladium Cross-coupling Boronic acids Microwave irradiation |
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