Efficient synthesis of substituted biaryl anilines and biaryl phenols via a Suzuki cross-coupling reaction |
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| Authors: | Bin Liu Kristofer K Moffett Rhoda W Joseph Bruce D Dorsey |
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| Institution: | Locus Pharmaceuticals, Inc., 4 Valley Square, 512 Township Line Road, Blue Bell, PA 19422, USA |
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| Abstract: | An efficient synthesis of biaryl building blocks with multiple point diversities via a Suzuki cross-coupling reaction using a commercially available preformed Pd catalyst 1 was reported. Substituted biaryl anilines and phenols were obtained in one step from commercially available aryl halides. |
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| Keywords: | Suzuki coupling Pd catalyst Biaryl building blocks |
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