Novel carboranylporphyrins for application in boron neutron capture therapy (BNCT) of tumors |
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| Authors: | J. Caleb Clark |
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| Affiliation: | Department of Chemistry, Louisiana State University, Baton Rouge, LA 70803, USA |
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| Abstract: | Condensation of a new carboranylpyrrole 1 with benzaldehydes leads to β-carboranylporphyrins 2 and 3 in good yields. These new porphyrins of high boron content (32-43%) have potential as boron delivery agents for BNCT. The X-ray structures of one β-carboranylporphyrin, of a carboranylpyrrole, and of a side-product are presented. |
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| Keywords: | BNCT Carborane Pyrrole Porphyrin Carboranylporphyrin |
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