Catalytic enantioselective fluorination of α-cyano acetates catalyzed by chiral palladium complexes |
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Authors: | Hye Ran Kim |
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Institution: | Department of Chemistry, Soonchunhyang University, Asan PO Box 97, Chungnam 336-600, Republic of Korea |
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Abstract: | The catalytic enantioselective electrophilic fluorination promoted chiral palladium complexes is described. Treatment of α-cyano acetates with N-fluorobenzenesulfonimide as the fluorine source under mild reaction conditions afforded the corresponding α-cyano α-fluoro acetates in high yields with excellent enantiomeric excesses (85-99% ee). |
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Keywords: | Chiral palladium complexes Fluorination Asymmetric reactions |
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