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Acetate aldol reactions of chiral oxocarbenium ions
Authors:Sandeep Kanwar
Institution:a Department of Chemistry and Center of Advanced Studies in Chemistry, Panjab University, Chandigarh 160 014, India
b Panacea Biotec Limited, Ambala-Chandigarh Highway, PO Lalru, Punjab 140 501, India
Abstract:Chiral oxocarbenium ions have been exploited to carry out highly diastereoselective and enantioselective acetate aldol addition reactions. The chiral auxiliary has been optimized to give the product with good diastereoselectivity.
Keywords:Acetate aldol reaction  Oxocarbenium ions  1  3-Allylic strain  Diastereoselective  Enantioselective
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