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Substrate-controlled diastereoselective aziridination of alkenes using 3-acetoxyaminoquinazolinone in the presence of hexamethyldisilazane
Authors:Sabri Ulukanli  Semistan Karabuga  Cavit Kazaz
Institution:a Department of Chemistry, Faculty of Science and Letters, University of Kafkas, 36100 Kars, Turkey
b Edinburgh Center for Protein Technology, Chemistry Department, University of Edinburgh, King’s Buildings, West Mains Road, Edinburgh, EH9 3JJ, UK
c Department of Chemistry, Faculty of Science and Letters, Ataturk University, 25240 Erzurum, Turkey
Abstract:8-Phenylmenthol derived α,β-unsaturated esters were aziridinated highly diastereoselectively using 3-acetoxyamino-2-ethylquinazolinone. The yields of these aziridines were greatly improved in the presence of hexamethyldisilazane.
Keywords:Aziridination  3-Acetoxyaminoquinazolinone  8-Phenylmenthol  Substrate-controlled diastereoselective aziridination
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