Copper-catalyzed allylic hydroxyamination and amination of alkenes with Boc-hydroxylamine |
| |
| Authors: | Biswajit Kalita |
| |
| Affiliation: | Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA |
| |
| Abstract: | Olefins react regioselectively with Boc-NHOH in the presence of Cu(I,II) salts to produce allyl-N(OH)(Boc) derivatives, apparently via the intermediacy of Boc-N O; yields and rates are dramatically improved by the addition of H2O2. The corresponding allylamine derivatives, allyl-NH(Boc), are formed selectively from Boc-NHOH/olefin with CuBr/P(OEt)3. |
| |
| Keywords: | Allylic amination Hydroxyamination Copper-catalyzed |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
