Asymmetric synthesis of (+)-L-733,060 |
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| Authors: | Youn-Jung Yoon |
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| Affiliation: | College of Pharmacy, SungKyunKwan University, Suwon 440-746, Republic of Korea |
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| Abstract: | A concise, stereocontrolled synthesis of (+)-L-733,060 was achieved. Key features involve diastereoselective oxazoline formation catalyzed by palladium(0) and intramolecular cyclization by catalytic hydrogenation of an oxazoline. |
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| Keywords: | Natural product L-733,060 Asymmetric synthesis Chiral oxazoline Intramolecular cyclization |
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