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1-Methylimidazole 3-N-oxide as a new promoter for the Morita-Baylis-Hillman reaction
Authors:Yu-Sheng Lin
Institution:Department of Chemistry, National Dong Hwa University, Shou-Feng, Hualien 974, Taiwan
Abstract:The Morita-Baylis-Hillman reaction of aldehydes with α,β-unsaturated ketones can be affected by the Lewis bases. We have found that 1-methylimidazole 3-N-oxide promoted the Morita-Baylis-Hillman reaction of various activated aldehyde compounds in non-solvent system. This is a mild reaction condition and requires no special equipment to give the Morita-Baylis-Hillman adducts.
Keywords:N-oxide  Morita-Baylis-Hillman reaction
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