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One-pot synthesis of triazole-linked glycoconjugates |
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| Authors: | Srinivas Chittaboina |
| Institution: | Department of Chemistry and Biochemistry, University of South Carolina, 631 Sumter Street, Columbia, SC 29208, USA |
| Abstract: | Highly efficient one-pot synthesis of 1,2,3-triazole-linked glycoconjugates was presented involving a Cu(I) catalyzed 1,3-dipolar cycloaddition as the key step. It offers a convenient route to prepare neoglycoconjugates derived from unprotected saccharides or peracetylated saccharides. |
| Keywords: | Click chemistry 1 3-Dipolar cycloaddition Glycosylation Neoglycoconjugate 1 2 3-Triazole Carbohydrate Bioconjugation |
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