Stereoselective synthesis of substituted N-heterocycles via sequential cross metathesis—reductive cyclization |
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| Authors: | Julian Gebauer |
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| Institution: | Technische Universität Berlin, Institut für Chemie, Strasse des 17. Juni 135, D-10623 Berlin, Germany |
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| Abstract: | A diastereoselective synthesis of substituted mono- and bicyclic-piperidine and pyrrolidine derivatives is presented, employing a highly selective cross metathesis (CM) reaction followed by a domino reduction-cyclization process. |
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| Keywords: | Cross metathesis Reductive amination Ruthenium catalyst Indolizidines Pyrrolizidines |
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