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A new entry to functionalized cycloalkylamines: diastereoselective intramolecular amidoalkylation of N,O-acetal TMS ether possessing allylsilane
Authors:Jong-Wha Jung  Seung-Yong Seo  Seung-Mann Paek  Young-Ger Suh
Institution:a College of Pharmacy, Seoul National University, Seoul 151-742, Korea
b College of Pharmacy, Chungbuk National University, Cheongju 361-763, Korea
Abstract:Highly diastereoselective cyclization (>20:1) as a new entry to functionalized cycloalkylamines has been conducted with acyclic N,O-acetal TMS ethers possessing an allylsilane moiety.
Keywords:Cycloalkylamine  Intramolecular amidoalkylation  N  O-Acetal TMS ether
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