Highly regioselective Diels-Alder reactions of 9-substituted anthracenes and 2-acetamidoacrylate: synthesis of conformationally constrained α-amino acids
Bristol-Myers Squibb Pharmaceutical Research Institute, Department of Chemistry, PO Box 4000, Princeton, NJ 08543, USA
Abstract:
The highly regioselective Diels-Alder reactions of 9-substituted anthracenes and 2-acetamidoacrylate afford a series of novel and conformationally constrained bicyclic bisaryl α-amino acids.