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Reaction of 5-aminotetrazole with vinamidinium salts: Formation of 2-(N, N-dimethylamino)-5-substituted pyrimidines |
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| Authors: | Hadj Ayed Med Adnen Khiari Jameleddine Ben Hassine Bechir |
| Institution: | Laboratoire de Synthèse Organique Asymétrique et Catalyse Homogène (01UR1201), Faculté des Sciences de Monastir, Monastir, 5019, Tunisia. |
| Abstract: | The cyclocondensation of vinamidinium salts with 5-aminotetrazole in basic media affords regiospecifically good yields of 2-(N, N-dimethylamino)-5- aryl-, arylsulfonyl- and 2-(N, N-dimethylamino)-5-formyl-pyrimidines, respectively. |
| Keywords: | 5-Aminotetrazole Cyclocondensation reaction Disubstituted pyrimidines Vinamidinium salts |
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