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Boronic acid-containing diarylpyrimidine derivatives as novel HIV-1 NNRTIs: Design,synthesis and biological evaluation
Institution:1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Ji’nan 250012, China;2. Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi 110007, India;3. Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, K.U. Leuven, Leuven B-3000, Belgium;4. China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, Ji’nan 250012, China;5. Suzhou Research Institute, Shandong University, Suzhou 215123, China
Abstract:
Keywords:HIV-1  NNRTIs  NNIBP  DAPY  Boronic acid  Molecular dynamics simulation
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