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Facile Synthesis of 5-Hydroxy-2-(2-phenylethyl)chromone
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关 键 词:5-Hydroxy-2-(2-phenylethyl)chromone  Synthesis  Baker-Venkataraman  rearrangement  Imperata  cylindrica  

Facile Synthesis of 5-Hydroxy-2-(2-phenylethyl)chromone
Authors:ZHANG Lan-ping WANG Ya-lou
Institution:Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, P. R. China
Abstract:5-Hydroxy-2-(2-phenylethyl)chromone(1) was synthesized from 2,6-dihydroxyacetophenone(7) obtained via four-steps resorcinol-reacting with phenylpropionic acid,the procedures involved are Baker-Venkataraman rearrangement and cyclization which are easy to conduct,the overall yield is 32%.
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