Reactions of 4-(2-aminothiazole-4-yl)-3-methyl-5-oxo-1-phenyl-2-pyrazoline. Synthesis of thiazolo[3,2- a ]pyrimidine and imidazo[2,1- b ]thiazole derivatives |
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| Authors: | Mohamed Salah K Youssef Ragaa A Ahmed Mohamed S Abbady Shawkat A Abdel-Mohsen and Ahmed A Omar |
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| Institution: | (1) University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, 160014, India |
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| Abstract: | 4-(2-Aminothiazol-4-yl)-3-methyl-5-oxo-1-phenyl-2-pyrazoline was synthesized via the reaction of 4-bromoacetyl-3-methyl-5-oxo-1-phenyl-2-pyrazoline with thiourea 7] and was transformed to related fused
heterocyclic systems. The antifungal and antibacterial studies revealed in some cases excellent biocidal properties. |
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