Efficient one-pot synthesis of functionalized piperidine scaffolds via ZrOCl2·8H2O catalyzed tandem reactions of aromatic aldehydes with amines and acetoacetic esters |
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| Authors: | Sarita MishraRina Ghosh |
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| Institution: | Department of Chemistry, Jadavpur University, Kolkata 700 032, India |
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| Abstract: | A highly efficient diastereoselective one-pot synthesis of functionalized piperidines has been developed based on an aqua-compatible ZrOCl2·8H2O catalyst via tandem reactions of aromatic aldehydes, amines, and acetoacetic esters. |
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| Keywords: | ZrOCl2· 8H2O One-pot synthesis Functionalized piperidine Tandem reaction |
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