Combinatorial libraries - from solution to 2D microarrays |
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Authors: | Díaz-Mochón Juan José Bialy Laurent Keinicke Lise Bradley Mark |
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Affiliation: | School of Chemistry, University of Southampton, Southampton, UK SO17 1BJ. |
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Abstract: | Enzymatic modifications of split and mix libraries were followed by "pulling down" onto a 2-dimensional DNA microarray, via PNA tagging; this allowed complete library interrogation of all members of the split and mix library. |
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