| Synthesis and Antibacterial Activity of New Tetracycfic Triazolothiadiazino Fluoroquinolones |
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| 作者姓名： | GuoQiangHU ZhongQuanZHANG WenLongHUANG HuiBinZHANG ShengTangHUANG |
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| 作者单位： | [1]MedicalCollegeofHenanUniversity,Kaifeng475004 [2]ChinaPharmaceuticalUniversity,Nanjing210009 |
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| 摘 要： | A series of novel 9-fluoro-10-(4-methylpiperazin-l-yl)-3-substituted-8-oxo-8H-1,2,4] triazolo3,4-b]thiadiazino6,5,4-ij]quinoline-7-carboxylic acids was prepared by a facile synthetic method and the in vitro antibacterial activity against Gram-postive (G^ ) and Gram negative (G^-) bacteria was primarily evaluated.
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| 关 键 词： | 抗生素 四环素 合成 抗菌活性 |
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