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Reference Parameters for Protein Hydrogen Exchange Rates
Authors:David Nguyen  Leland Mayne  Michael C Phillips  S Walter Englander
Institution:1.Johnson Research Foundation, Department of Biochemistry and Biophysics, Perelman School of Medicine,University of Pennsylvania,Philadelphia,USA;2.Children’s Hospital of Philadelphia,Philadelphia,USA
Abstract:The analysis of many hydrogen exchange (HX) experiments depends on knowledge of exchange rates expected for the unstructured protein under the same conditions. We present here some minor adjustments to previously calibrated values and a stringent test of their accuracy.
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