Spectrofluorimetric determination of acrivastine in spiked human urine and pharmaceuticals |
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Authors: | Fernández Rut Bello Miguel Angel Callejón Manuel Jiménez Juan Carlos Guiraúm Alfonso |
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Institution: | Department of Analytical Chemistry, Faculty of Chemistry, 41012 Seville, Spain. |
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Abstract: | A spectrofluorimetric method to determine acrivastine is proposed and applied to its determination in human urine and pharmaceuticals. The fluorimetric method allows the determination of 58-2000 ng ml(-1) of acrivastine in aqueous solutions containing acetic acid-sodium acetate buffer (pH 6.5) with lambda(exc)=230 nm and lambda(em)=380 nm. |
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