Enforcing solution phase nanoscopic aggregation in a palindromic tripeptide |
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| Authors: | Prasad K Krishna Purohit C S Jain Alok Sankararamakrishnan R Verma Sandeep |
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| Affiliation: | Department of Chemistry, Indian Institute of Technology-Kanpur, Kanpur-208016 (UP), India. |
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| Abstract: | C-terminal dimerization of a tripeptide palindrome afforded fibrillation in solution through an assembly probably driven by hydrogen bonding and hydrophobic contributions; such an approach provides an expeditious entry into fabrication of fibrillating peptides from non-fibrillating peptide sequences. |
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