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Polyhydroxylated nortropanes starting from D-glucose: Synthesis of homochiral (+) and (−)-calystegines B2 |
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| Authors: | O Duclos M Mondange A Durault JC Depezay |
| Institution: | Université René Descartes, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, associé au CNRS, 45 rue des Saints-Pères, 75270 Paris cedex 06, France |
| Abstract: | The cycloheptano-isoxazoline 1, prepared from D-glucose, is converted to 6,7-dideoxy cycloheptitols which are suitable precursors for the synthesis of enantiomerically pure (+) and (−)-Calystegines B2. |
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