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Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol
Authors:Tamura S  Fukamiya N  Mou X Y  Mukainaka T  Tokuda H  Nishino H  Tagahara K  Koike K  Lee K H  Okano M
Institution:Department of Interdisciplinary Studies of Natural Environment, Faculty of Integrated Arts and Sciences, Hiroshima University, Higashi-Hiroshima, Japan.
Abstract:Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.
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