Highly efficient Lewis acid-catalysed Pictet-Spengler reactions discovered by parallel screening |
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| Authors: | Srinivasan Natarajan Ganesan A |
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| Affiliation: | Combinatorial Centre of Excellence, Department of Chemistry, University of Southampton, Southampton, United Kingdom SO17 1BJ. |
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| Abstract: | High yielding Lewis acid-catalysed one-pot Pictet-Spengler reactions of tryptophan methyl ester and tryptamine with aliphatic and aromatic aldehydes were achieved in short reaction times with the aid of microwave irradiation. |
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