Lipoxygenase inhibiting ethyl substituted glycoside from Symplocos racemosa |
| |
Authors: | Abbasi Muhammad Athar Ahmad Viqar Uddin Zubair Muhammad Nawaz Sarfraz A Lodhi Muhammad Arif Farooq Umar Choudhary M Iqbal |
| |
Affiliation: | HEJ Research Institute of Chemistry, International Center for Chemical Sciences University of Karachi, Karachi 75270, Pakistan. atrabbasi@yahoo.com |
| |
Abstract: | Phytochemical investigation of Symplocos racemosa resulted in the isolation of a new ethyl substituted glycoside, 1-ethyl brachiose-3'-acetate (1) along with four known compounds ketochaulmoogric acid (2), nonaeicosanol (3), triacontyl palmitate (4) and methyl triacontanoate (5). The substitution of ethyl group on 1 was natural because during the course of extraction and purification ethanol was not used. The structural elucidation of the isolated compounds was based primarily on 1D- and 2D-NMR analysis, including COSY, HMQC, and HMBC correlations. The glycoside 1 and triacontyl palmitate (4) displayed the inhibitory potential against lipoxygenase and urease enzyme, respectively. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|