The effect of water vapour on the cyclodextrin-solute interaction in gas-solid chromatography

The effect of water vapour on the interaction between the solutes and a cyclodextrin was studied chromatographically in a gas/solid system. It has been shown that all the sorbates capable of forming inclusion complexes with -CD are affected by the presence of water, in contrast to the sorbates that do not interact with -CD, which are unaffected. The measurements were carried out with the cyclodextrin deposited on a solid carrier (Chromosorb W) and with water vapour contained in the mobile phase. Some advantages of this system have been demonstrated for an analytical application.Presented at the Fourth International Symposium on Inclusion Phenomena and the Third International Symposium on Cyclodextrins, Lancaster, U.K., 20–25 July 1986.