A convenient one-pot synthesis of ethylene blue |
| |
Authors: | Jeremy A. Cody Christian S. LarrabeeMichael D. Clark Sofiya HlynchukJacob A. Tatum |
| |
Affiliation: | Department of Chemistry, Rochester Institute of Technology, 85 Lomb Memorial Drive, Rochester , NY 14623-5603, USA |
| |
Abstract: | We have developed an efficient one-pot, two-step preparation of ethylene blue by eliminating aqueous work-ups and cumbersome purification techniques. Our procedure generates ethylene blue in good overall yields of 45-56% with approximately 95% purity, which is uncommon for the synthesis of a phenothiazinium salt. Due to its unique properties, ethylene blue has great potential for a broad range of biological applications and, as a result, an efficient procedure for the synthesis of ethylene blue is critical. |
| |
Keywords: | One-pot Ethylene blue Synthesis Phenothiazinium Dye |
本文献已被 ScienceDirect 等数据库收录! |
|