|
|||||
|
|
Electrochemical Aziridination by Alkene Activation Using a Sulfamate as the Nitrogen Source |
|
| Authors: | Jin Li Wenhao Huang Jingzhi Chen Lingfeng He Xu Cheng Guigen Li |
| Institution: | 1. Institute of Chemistry and Biomedical Sciences, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, National Demonstration Center for Experimental Chemistry Education, Nanjing University, Nanjing, China;2. State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing, China;3. State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin, China;4. Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA |
| Abstract: | The first direct aziridination of triaryl‐substituted alkenes was achieved by means of an electrochemical process that could extend to multisubstituted styrenes. Specifically, hexafluoroisopropanol sulfamate was used as a nucleophilic nitrogen source. Mechanistic experiments suggest that this electrochemical process proceeds by stepwise formation of two C?N bonds through reactions between cationic carbon species and the sulfamate. |
| Keywords: | alkenes aziridines electrochemistry radicals synthetic methods |