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Alkyl Ethers as Traceless Hydride Donors in Brønsted Acid Catalyzed Intramolecular Hydrogen Atom Transfer |
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| Authors: | Dhika Aditya Gandamana Dr Bin Wang Dr Ciputra Tejo Dr Benoit Bolte Prof Fabien Gagosz Prof Shunsuke Chiba |
| Institution: | 1. Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore;2. Département de Chimie, UMR 7652 and 7653 CNRS, Ecole Polytechnique, Palaiseau, France;3. Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Canada |
| Abstract: | A new protocol for the deoxygenation of alcohols and the hydrogenation of alkenes under Brønsted acid catalysis has been developed. The method is based on the use of either a benzyl or isopropyl ether as a traceless hydrogen‐atom donor, and involves an intramolecular hydride transfer as a key step, which is achieved in a regio‐ and stereoselective manner. |
| Keywords: | alcohols alkenes Brø nsted acid hydrogen-atom transfer reduction |