| 原子力显微镜在生物大分子结构研究中的应用进展 |
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| 引用本文： | 鲍幸峰,方积年.原子力显微镜在生物大分子结构研究中的应用进展[J].分析化学,2000,28(10):1300-1307. |
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| 作者姓名： | 鲍幸峰 方积年 |
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| 作者单位： | 中国科学院上海药物研究所,上海,200031 |
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| 摘 要： | 评述了原子力显微镜（ａｔｏｍｉｃ ｆｏｒｃｅ ｍｉｃｒｏｓｃｏｐｙ，ＡＦＭ）的成镜模式与探针技术的发展以及在脱氧核糖核酸、蛋白质和多糖等生物大分子结构研究中的应用进展，并展望了原子力显微镜在此领域的发展前景。
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| 关 键 词： | 原子力显微镜 探针 蛋白质 多糖 DNA 结构研究 |
The Advances of Applications in Studying the Structures of Biological Macromolecules by Atomic Force Microscopy |
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| Bao Xingfeng,Fang Jinian.The Advances of Applications in Studying the Structures of Biological Macromolecules by Atomic Force Microscopy[J].Chinese Journal of Analytical Chemistry,2000,28(10):1300-1307. |
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| Authors: | Bao Xingfeng Fang Jinian |
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| Institution: | Bao Xingfeng
,Fang Jinian
(Shanghai lnstitute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031) |
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| Abstract: | The imaging mode and the development of tip technologies of atomic force microscopy (AFM) are briefly surveyed. A review of the application of AFM in studying the structures of biological macromolecules including deoxyribonucleic acid (DNA), proteins, polysaccharides etc. is presented. And the future prospect of AFM in this field is outlooked. |
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| Keywords: | Atomic force microscopy tip deoxyribonucleic acid proteins polysaccharides |
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