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Study on biodegradable polymer. 3. Synthesis and characterization of poly(DL-lactic acid)-co-poly(ethylene glycol)-co-poly(L-lysine) copolymer
Authors:Xianmo DengYu Liu  Minglong Yuan
Affiliation:Academia Sinica, Chengdu Institute of Organic Chemistry, P.O. Box 415, Chengdu 610041, China
Abstract:
The synthesis of poly(DL-lactic acid)-co-poly(ethylene glycol)-co-poly(L-lysine) copolymer was investigated by the reaction of amino acid-N-carboxy anhydride with lactic acid anhydrosulphite and methoxypolyoxyethylene amine (MPEG-NH2). The successful synthesis was obtained after adding dibutylmegnesium into the system. The product was proved to be copolymer. The solubility of the polymer revealed that it was ionic polymer.
Keywords:Synthesis   Lactic acid anhydrosulphite   Amino acid-N-carboxyl anhydride   Methoxypolyoxyethylene amine
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